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There are several matches for 'probable DNA binding protein'.
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6018 matches
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organism
protein
1)
Homo sapiens
NONO - Non-POU domain-containing octamer-
binding
protein
;
DNA
- and RNA
binding
protein
, involved in several nuclear processes.
Binds
the conventional octamer sequence in double-stranded
DNA
. Also
binds
single-stranded
DNA
and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing,
probably
as a heterodimer with SFPQ. Interacts with U5 snRNA,
probably
by
binding
to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. Together with PSPC1, required for the formation of nuclear paraspeckles. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclea [...]
[a.k.a. ENST00000454976.1, ENST00000471419, NonO protein]
2)
Homo sapiens
ZBTB32 - Zinc finger and BTB domain-containing
protein
32;
DNA
-
binding
protein
that
binds
to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor.
Probably
exerts its repressor effect by preventing GATA3 from
binding
to
DNA
. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).
[a.k.a. ENST00000392197.6, CCDS12471, ZBTB32-206]
3)
Homo sapiens
RBMS1 - RNA-
binding
motif, single-stranded-interacting
protein
1; Single-stranded
DNA
binding
protein
that interacts with the region upstream of the MYC gene.
Binds
specifically to the
DNA
sequence motif 5'-[AT]CT[AT][AT]T-3'.
Probably
has a role in
DNA
replication.
[a.k.a. MSSP-2, E7ETU5, ENST00000464200.1]
4)
Homo sapiens
ZCCHC3 - Zinc finger CCHC domain-containing
protein
3; Nucleic acid-
binding
protein
involved in innate immune response to
DNA
and RNA viruses.
Binds
DNA
and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS. Acts as a co-sensor for recognition of double-stranded
DNA
(dsDNA) by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and
DNA
virus.
Binds
dsDNA and
probably
acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation. Promo [...]
[a.k.a. Q9NUD5, NX_Q9NUD5, uc032oxz.2]
5)
Homo sapiens
SON -
Protein
SON; RNA-
binding
protein
that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and
DNA
-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG.
Probably
acts by facilitating the interaction between Serine/arginine-rich
proteins
such as SRSF2 and the RNA polymerase II. Also
binds
to
DNA
;
binds
to the consensus
DNA
sequence: 5'-GA[GT]AN[CG][AG]CC-3'. May indirectly repress hepatitis B virus (HBV) core prom [...]
[a.k.a. ENSP00000321123, EAX09821.1, CH471079]
6)
Homo sapiens
MEIS2 - Homeobox
protein
Meis2; Involved in transcriptional regulation.
Binds
to HOX or PBX
proteins
to form dimers, or to a
DNA
-bound dimer of PBX and HOX
proteins
and thought to have a role in stabilization of the homeoprotein-
DNA
complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex
binds
to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex
DNA
-
binding
.
Probably
in [...]
[a.k.a. Homeobox protein Meis2, MEIS2-225, NM_002399]
7)
Homo sapiens
RPA4 - Replication
protein
A 30 kDa subunit; As part of the alternative replication
protein
A complex, aRPA,
binds
single-stranded
DNA
and
probably
plays a role in
DNA
repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal
DNA
replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by
DNA
polymerase alpha but could support
DNA
polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
[a.k.a. R-HSA-69278, RFA4_HUMAN, ENSG00000204086]
8)
Homo sapiens
CHD7 - Chromodomain-helicase-
DNA
-
binding
protein
7;
Probable
transcription regulator. Maybe involved in the in 45S precursor rRNA production.
[a.k.a. ENST00000532149, CHD7-210, D0VBA5]
9)
Homo sapiens
TGIF2 - Homeobox
protein
TGIF2; Transcriptional repressor, which
probably
repress transcription by
binding
directly the 5'-CTGTCAA-3'
DNA
sequence or by interacting with TGF-beta activated SMAD
proteins
.
Probably
represses transcription via the recruitment of histone deacetylase
proteins
.
[a.k.a. R-HSA-170834, TGF-beta-induced transcription factor 2, ENSP00000476174]
10)
Homo sapiens
MYF6 - Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts.
Probable
sequence specific
DNA
-
binding
protein
.
[a.k.a. myogenic factor 6, ENSP00000228641, P23409]
11)
Homo sapiens
MYF5 - Myogenic factor 5; Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle- specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts.
Probable
sequence specific
DNA
-
binding
protein
.
[a.k.a. EAW97368.1, UPI000013C8D9, Myf-5]
12)
Homo sapiens
ZBTB42 - Zinc finger and BTB domain-containing
protein
42; Transcriptional repressor. Specifically
binds
DNA
and
probably
acts by recruiting chromatin remodeling multiprotein complexes.
[a.k.a. ENST00000342537, ENSG00000179627, NP_001131073]
13)
Homo sapiens
MLLT10 -
Protein
AF-10;
Probably
involved in transcriptional regulation. In vitro or as fusion
protein
with KMT2A/MLL1 has transactivation activity.
Binds
to cruciform
DNA
. In cells,
binding
to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation.
[a.k.a. XM_024448186.1, uc001iqs.4, ENSP00000488569]
14)
Homo sapiens
HABP4 - Intracellular hyaluronan-
binding
protein
4; RNA-
binding
protein
that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates
DNA
-
binding
activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation.
Binds
(via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation,
probably
at the initiation step. Seems to play a role in PML-nuclear bodies formation.
[a.k.a. hyaluronan binding protein 4, ENSP00000364398, Hyaluronan binding protein 4]
15)
Homo sapiens
CTCFL - Transcriptional repressor CTCFL; Testis-specific
DNA
binding
protein
responsible for insulator function, nuclear architecture and transcriptional control, which
probably
acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly
binds
the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This
probably
leads to recruit de novo
DNA
methyltransferases a [...]
[a.k.a. DQ778116, ENSP00000476398, OMIM:607022]
16)
Homo sapiens
HMGB2 - High mobility group
protein
B2; Multifunctional
protein
with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone
protein
involved in transcription, chromatin remodeling and V(D)J recombination and
probably
other processes.
Binds
DNA
with a preference to non- canonical
DNA
structures such as single-stranded
DNA
. Can bent
DNA
and enhance
DNA
flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor
binding
and/or bring [...]
[a.k.a. R-HSA-109581, UPI0001D3BA60, R-HSA-140342]
17)
Homo sapiens
BHLHE22 - Class E basic helix-loop-helix
protein
22; Inhibits
DNA
binding
of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes,
probably
by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not
bind
to
DNA
(By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealiza [...]
[a.k.a. ENST00000321870, ENSG00000180828, ENSP00000318799]
18)
Homo sapiens
E2F3 - Transcription factor E2F3; Transcription activator that
binds
DNA
cooperatively with DP
proteins
through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in
DNA
replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3
binds
specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis,
probably
through the repression of CEBPA
binding
to its target gene promoters (By similarity).
[a.k.a. E2F transcription factor 3, R-HSA-69278, R-HSA-162582]
19)
Homo sapiens
G3BP1 - Ras GTPase-activating
protein
-
binding
protein
1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the
DNA
- triggered cGAS/STING pathway by promoting the
DNA
binding
and activation of CGAS. Enhances also DDX58-induced type I interferon production
probably
by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial
DNA
and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, R [...]
[a.k.a. ENSP00000430045, HGNC:30292, E5RIZ6]
20)
Homo sapiens
ALX1 - ALX homeobox
protein
1; Sequence-specific
DNA
-
binding
transcription factor that
binds
palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most
probably
regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1. Belongs to the paired homeobox family.
[a.k.a. CCDS9028.1, HPA001598, NM_006982.3]
6018 matches
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